dic(7;9)(p11-12;p12-13) PAX5/LOC392027

Nonrandom involvement of the 12p12 breakpoint in chromosome abnormalities of childhood acute lymphoblastic leukemia.

We studied the presenting clinical and biologic features of 23 children with acute lymphoblastic leukemia (ALL) whose leukemic marrow karyotypes contained abnormalities involving the short arm of chromosome 12. Nineteen of the abnormalities were assigned to the 12p12 breakpoint. The median age of the children was 5 years (range 2 to 13 years) and their initial leukocyte counts ranged from 1,800...

Tids_a_119261 13..13 ++

Purpose. To develop a scale to measure (social) participation for use in rehabilitation, stigma reduction and social integration programmes. Method. A scale development study was carried out in Nepal, India and Brazil using standard methods. The instrument was to be based on the Participation domains of the International Classification of Functioning, Disability and Health (ICF), be cross-cultu...

A13 13..13

Two papers examining mental incapacity among psychiatric in-patients are presented in the Journal this month – one investigation focuses on assessment reliability (Cairns et al, pp. 372–378) and one on the prevalence and predictors of incapacity (Cairns et al, pp. 379–385). The authors find that the MacArthur Competence Assessment Tool for Treatment (MacCAT– T) can be used reliably to assess ca...

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